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Loss of Appetite, Weight Loss, Wasting Syndromes

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See also: Megace, Megestrol


Wasting Syndrome & Weight Loss, An Introduction,"Weight loss and wasting syndrome are two AIDS-related complications that, if not adequately treated, can be life threatening. Even though anti-HIV therapies have helped reduce the risk of weight loss and wasting syndrome, both problems still occur. According to a study reported in late 1997, as many as 25% of HIV-positive people receiving triple-drug anti-HIV therapy still experience some degree of weight loss and/or wasting."


Anticatabolic and Anabolic Strategy, (Nutrition),"The maintenance of optimum nutrition through both the stress response or catabolic phase and the recovery or anabolic phase is the most important strategy to decrease lean mass loss and to regain lost lean mass."


Standards, Options and Recommendations (SOR) for the use of appetite stimulants in oncology Bulletin du Cancer. Vol. 87, Issue 4, April 2000: 315-28, Standards, Options and Recommendations:"Summary: Context. The “Standards, Options and Recommendations” (SOR) project, started in 1993, is a collaboration between the Federation of the French Cancer Centres (FNCLCC), the 20 French Cancer Centres and specialists from French Public Universities, General Hospitals and Private Clinics. The main objective is the development of clinical practice guidelines to improve the quality of health care and outcome for cancer patients."


Study on Loss of Appetite, BEING ALIVE; May 1995, Gary E. Costa:"The CDC has stated that weight loss of greater than 10% of body weight is the index diagnosis for almost one-fifth of AIDS cases. Realizing the importance of weight management as it relates to successful recovery from opportunistic infections, medical providers are increasingly including nutritional supplements, hormone replacement, and/or appetite stimulants as part of treatment. There has been increasing literature on loss of appetite, and the dramatic effects it has on life expectancy."


Wasting Syndrome & Weight Loss Can It Be Treated?"As the name "syndrome" implies, wasting is a problem related to many possible causes. Any or all of the problems discussed previously can contribute to HIV-related wasting, sometimes gradually throughout the course of disease or sometimes rapidly in the presence of an opportunistic infection (OI). Given the numerous possible causes of wasting syndrome, it should come as no surprise that treatments for wasting are equally complex and, unfortunately, cannot be universally prescribed. No "standard of care" for wasting exists; in fact, there is little consensus regarding the best way to prevent and treat wasting, especially muscle loss."


Appetite Stimulation/Cachexia, Medical Marijuana,"It has been shown that there is a strong relationship between smoking marijuana and increased frequency and amount of eating. Survey data on appetite stimulation (Haines and Green 1970) (N = 131) showed that 91 percent of marijuana users eat every time they smoke. Tart (1970) found that 93 percent of marijuana users (131) reported that marijuana made them enjoy eating very much and that they consequently ate a lot more. Foltin and colleagues (1986) reported that marijuana users eat more often. A study by Farrow and associates (1987) reported no hematologic changes or signs of nutrient deficiencies in marijuana users."


Appetite Stimulation: Medicinal Marijuana, Marinol, and Megace by Nelson Vergel and Michael Mooney (Issue # 7, October, 1998):"Appetite stimulants can be an important part of the optimal approach to increasing lean body mass in HIV. However, all appetite stimulants are not equal in their effects on your overall health and well-being. The first drug used for appetite in the early years of AIDS was Megace. The Medibolics article on Megace showed us that Megace should probably be relegated to the status of the problematic dinosaur drug that it is."


Appetite Stimulants for the Starving In-Kind Donations: Not Always Kind to Recipients, The American Institute of Philanthropy:"It is easy to be impressed when reading of the large quantities of donated medical supplies and drugs that charities and businesses send to areas devastated by wars, earthquakes and other disasters. These donations usually help to alleviate human suffering but sometimes they cause additional problems."
American Institute of Philanthropy
3450 Lake Shore Drive Suite 2802 P.O. Box 578460 Chicago, Illinois 60657
Phone: (773) 305-0414 Fax: (773) 305-0417 E-mail:




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Last updated by Andrew Lopez, RN on March 13, 2023

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