Nursing & Healthcare Directories on: The Nursefriendly
Direct Patient Care Resources
Birth Defects, Congenital Abnormalities,
Larsons Syndrome (Larsens)

Related Links: Birth Defects, http://www.nursefriendly.com/defects


Also known as: Desbuquois Syndrome Sinding-Larsen-Johansson Disease

The Shortcut URL To This Section Is: http://www.nursefriendly.com/larsens


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Specialneedsnurse.org, Forums:"The information place for special needs. I hope to provide a place for nurses, teachers and parents to find links, articles, continuing education on various developmental disabilities such as mental retardation, autism spectrum disorder, pdd, Rett's syndrome, Asperger's syndrome and so many more. I hope to also provide a place to chat and exchange information regarding nursing, parenting, and teaching problems/issues of children and adults with special needs on the (Click on Bulletin board-) Bulletin Board. "
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Larsen's Syndrome Support Group, 24Dr.com:"The Larsen's Syndrome Support Group is a self-help group of families affected by the syndrome. The families share experiences and difficulties. The group has some literature available including comments regarding management of problems concerning extremity and spinal deformities from Loren J Larsen. Literature also includes Associated Findings in Larsen Syndrome."
Larsen's Syndrome Support Group
7 Littleworth Lane Esher Surrey KT10 9PF Phone: 01372 467061
http://www.24dr.com/reference/contact/group/larsens_syndrome.htm

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Larsen's Syndrome, Gasnet:"Multiple congenital joint dislocations Cartilage weakness in ribs, epiglottis, and arytenoids Subglottic stenosis, tracheomalacia Potentially difficult airway C-spine evaluation Congenital heart disease."
http://gasnet.med.yale.edu/pediatric-syndromes/larsen.php

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Larsen's syndrome, Question: Please may I have some information on Larsen's syndrome? IAfrica.com:"Answer: Larsen's syndrome describes an inherited condtion in which a child is born with multiple congenital dislocations, a prominent forehead, depressed nasal bridge and wide-spaced eyes. The children have clubfeet, dislocation of both knees, hips, and elbows, and short, cylindrical fingers. Some also have a cleft palate, hydrocephalus and abnormalities of the spine."
webmaster@gasnet.org
http://health.iafrica.com/doconline/qa/genetic/larsens.htm

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General Discussion, Larsen Syndrome, National Organization for Rare Disorders, Inc.:"Larsen Syndrome is a rare genetic disorder in which associated features may vary greatly in range and severity from case to case. However, primary features may include multiple joint dislocations; foot deformities; non-tapering, cylindrically shaped fingers; and/or an unusual facial appearance. In some cases, additional features may be present, such as short stature, additional skeletal abnormalities, incomplete closure of the roof of the mouth (cleft palate), heart defects, hearing impairment, mental retardation, and/or other abnormalities.
National Organization for Rare Disorders, Inc.
ddorman@rarediseases.org or call (202) 496-1296.
http://www.rarediseases.org/search/rdbdetail_abstract.html?disname=Larsen%20Syndrome

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Features Listed For LARSEN SYNDROME McKusick, UK Human Genome Mapping Project Resource Centre:"Abnormal auditory ossicles Anal atresia/stenosis Bipartite calcaneus Broad thumbs/pollices Cataract Cleft palate Cleft upper lip (non-midline) Club foot/hindfoot, valgus Club foot/hindfoot, varus Deafness, conductive Dislocated elbow Dislocated knee Extra carpals Fusion of vertebrae Hypertelorism Hypoplastic or absent fibula Joint laxity Malformed uterus Multiple joint dislocation Polydactyly/bifid thumb/pollex Radio-ulnar synostosis Segmentation defects of spine Short/hypoplastic metacarpals."
http://www.hgmp.mrc.ac.uk/dhmhd-bin/hum-look-up?972

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Idaho Boy Suffers From Rare Joint Disease, March 10, 2000 (News Story):"Can you imagine living with muscles and joints that act like rubber bands? It's a rare, terminal disease called Larson's Syndrome. A little boy from Emmet, Idaho, suffers from it. He's now at Primary Children's Medical Center. Carole Mikita tells Anthony Hardman's story."
http://web.ksl.com/dump/news/cc/larsons.htm

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Larsen Syndrome, By: Bonnie Bieganski (Personal Homepage):"Although the first case of Larsen Syndrome was found to be in the year of 1929, it was in 1950 that Dr. Loren Larsen described a syndrome that was found to be present at birth, which he named after himself. He described it as being characterized by multiple dislocations of the major joints, deformities of the feet and hands, abnormal segmentation of the spine, and by an unusual facial appearance which include a flat nasal bridge, wide-spaced eyes, and a prominent forehead. Airway problems, caused by lack of rigidity of the upper airway, was an additional finding in Larsen Syndrome. Before Dr. Larsen named this syndrome, patients were misdiagnosed as having Arthrogryposis."
http://www.stormloader.com/nita/le.html

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Larsens syndrome and Shadee (Personal Homepage):"Shadee was born on Dec24th at 750am. He was not breathing and was being resusitated as I watched and cried. He finally began to breath but was wraped up and immediately sent to the nursery. I was told he had some deformities and the doctor would come and speak with me. My husband had explained that his knees were backwards and his feet were bent."
http://www.geocities.com/ehabm27/index.html

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Last updated by Andrew Lopez, RN on March 13, 2023


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